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Author Topic: Crocodile Blood May Yield HIV Drug
Hephaestion
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posted 22 August 2005 04:41 AM      Profile for Hephaestion   Author's Homepage        Edit/Delete Post  Reply With Quote 
Wowsers!

quote:
Scientists in Australia's Northern Territory say the blood from crocodiles may help in developing powerful new antibodies for humans.

Australia's ABC television reports that researchers from Darwin's Crocodylus Park are collecting blood samples from the giant reptiles and hope to isolate the antibodies that make them immune from most diseases.

One of those antibodies appears to destroy HIV the broadcaster reports.

Professor Mark Merchant, an American biochemist working with the Australian researchers said that in addition to being immune from most diseases crocodiles often lose limbs in territorial fighting but rarely succumb to any illnesses.

Merchant said that the team hopes to isolate the antibody chemicals that are in crocodile blood and reproduced them for use in drugs for humans.

From: goodbye... :-( | Registered: Dec 2003  |  IP: Logged
Nanuq
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posted 22 August 2005 07:15 AM      Profile for Nanuq   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
The hardest part of the process is getting the crocodile to donate the blood.
From: Toronto | Registered: Feb 2005  |  IP: Logged
Crippled_Newsie
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posted 22 August 2005 08:20 AM      Profile for Crippled_Newsie     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by Nanuq:
The hardest part of the process is getting the crocodile to donate the blood.

...of course, if the crocodile is male and has had sex with a man (or, presumably, another male crocodile) in the last decade, he cannot donate.


From: It's all about the thumpa thumpa. | Registered: Oct 2004  |  IP: Logged
swirrlygrrl
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posted 22 August 2005 09:45 AM      Profile for swirrlygrrl     Send New Private Message      Edit/Delete Post  Reply With Quote 
Just in the last decade, Tape_342? I thought the permanent deferral was for MSM anytime after the mid-70s? *grrrr*

Especially annoying as CBS just reduced the deferral for those who have sex with an opposite sex partner whose sexual history they don't know from 12 to 6 months.

The whole thing is stupid and pisses me off A LOT. Totally discriminatory.


From: the bushes outside your house | Registered: Feb 2002  |  IP: Logged
HerculesRockefeller
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posted 22 August 2005 12:18 PM      Profile for HerculesRockefeller     Send New Private Message      Edit/Delete Post  Reply With Quote 
PETA will freak over this. I mean, it's not like the crocodile gave up its blood voluntarily.
From: Canada | Registered: Aug 2005  |  IP: Logged
deBeauxOs
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posted 22 August 2005 12:34 PM      Profile for deBeauxOs     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by Nanuq:
The hardest part of the process is getting the crocodile to donate the blood.
Hee! I just had a flash of a Gary Larsen-style cartoon - a blood-donor's clinic for crocs with the volunteers sitting at tables afterwards, eating various putrified snacks.

From: missing in action | Registered: Aug 2005  |  IP: Logged
Mr. Magoo
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posted 22 August 2005 12:35 PM      Profile for Mr. Magoo   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
Ya, better a human die slowly than an animal with a brain the size of a walnut donate blood against its will.
From: ø¤°`°¤ø,¸_¸,ø¤°`°¤ø,¸_¸,ø¤°°¤ø,¸_¸,ø¤°°¤ø, | Registered: Dec 2002  |  IP: Logged
Gir Draxon
leftist-rightie and rightist-leftie
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posted 22 August 2005 01:00 PM      Profile for Gir Draxon     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by HerculesRockefeller:
PETA will freak over this. I mean, it's not like the crocodile gave up its blood voluntarily.

Well then they should make sure to have a WAAAHmbulance on-site in case of emergency.


From: Arkham Asylum | Registered: Feb 2003  |  IP: Logged
Krago
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posted 22 August 2005 01:07 PM      Profile for Krago     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by swirrlygrrl:
Just in the last decade, Tape_342? I thought the permanent deferral was for MSM anytime after the mid-70s? *grrrr*

Especially annoying as CBS just reduced the deferral for those who have sex with an opposite sex partner whose sexual history they don't know from 12 to 6 months.

The whole thing is stupid and pisses me off A LOT. Totally discriminatory.


Stupid question: MSM? CBS?

(I thought MSM stood for Mainstream Media, which would explain CBS, but in this context it makes no sense.)


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swirrlygrrl
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posted 22 August 2005 01:28 PM      Profile for swirrlygrrl     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Ya, better a human die slowly than an animal with a brain the size of a walnut donate blood against its will.

Er, what relevance is the size of the brain of the animal in question, really? Would you be more likley to take PETAs side if the animal in question had a brain the size of a grapefruit, or a loaf of bread, or a basketball? I think for most people who would disagree with PETA's position, the concern is that the blood in question comes from a non-human, not the size of the brain of the animal.

I also think its more than a bit disingenuous to refer to the animal "donating" blood (when not speaking in a tongue in cheek sense) - I'd imagine they will be killed, and the blood will be harvested. People can make whatever judgement they want on whether the rights of the animal or the people who benefit from the treatment, but I do have an issue when people don't want to face what their choice means.

*edited to add*

quote:
Stupid question: MSM? CBS?

No such thing! I apologize for random acronym use (what can I say? I work for the government!)

MSM = men who have sex with men
CBS = Canadian Blood Services

[ 22 August 2005: Message edited by: swirrlygrrl ]


From: the bushes outside your house | Registered: Feb 2002  |  IP: Logged
deBeauxOs
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posted 22 August 2005 01:49 PM      Profile for deBeauxOs     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Originally posted by Mr. Magoo:
Ya, better a human die slowly than an animal with a brain the size of a walnut donate blood against its will.
Watch it, Mr Magoo, your reptilian brain is speaking up again.
quote:
Originally posted by swirrlygrrl:
I also think its more than a bit disingenuous to refer to the animal "donating" blood (when not speaking in a tongue in cheek sense) - I'd imagine they will be killed, and the blood will be harvested.
Not said in defense of the scientific, but it is more likely that they would have two crocodiles in captivity that they would regularly "bleed" as living animals produce more blood. Crocs as well as being a protected species, are notoriously difficult to catch. More efficient not to kill them, I would guess.

Here is another issue that riles me up. Do you remember, some years ago, that it was discovered that there were sex workers in Nairobi who seemed to be 'immune' to HIV? Big Pharma was very interested in studying these women because of the possibility of using their specific genetic material to create a vaccine. Now here is the thing: it appeared that patent rights for pharmaceutical products derived from their DNA could be legally secured, as long as the company obtained a waiver from the original donors.

Nothing about the Kenya women has been in the media in recent years, though the issue of who "owns" individual DNA - for commercial exploitation - has not been resolved, I think.


From: missing in action | Registered: Aug 2005  |  IP: Logged
Mr. Magoo
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posted 22 August 2005 02:15 PM      Profile for Mr. Magoo   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Er, what relevance is the size of the brain of the animal in question, really?

It correlates with cognitive functions, and so to whatever degree you believe an animal suffers under any given treatment, it's going to suffer more if it has a larger brain to recognize that suffering.

It's why nobody talks about cruelty to plants, right? The assumption that plants lack any self-awareness or consciousness?

quote:
People can make whatever judgement they want on whether the rights of the animal or the people who benefit from the treatment, but I do have an issue when people don't want to face what their choice means.

Why would you think I wasn't being tongue in cheek?

Anyway, here's my idea, which should satisfy all the "animal rights" kooks: we approach the crocodiles with a mutual non-aggression pact. No crocodile harms a human, and in return, no human harms a crocodile. If either side fails to abide by this simple treaty, it's "open season".


From: ø¤°`°¤ø,¸_¸,ø¤°`°¤ø,¸_¸,ø¤°°¤ø,¸_¸,ø¤°°¤ø, | Registered: Dec 2002  |  IP: Logged
chubbybear
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posted 22 August 2005 02:41 PM      Profile for chubbybear        Edit/Delete Post  Reply With Quote 
oops

[ 22 August 2005: Message edited by: chubbybear ]


From: nowhere | Registered: Jul 2005  |  IP: Logged
chubbybear
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posted 22 August 2005 02:45 PM      Profile for chubbybear        Edit/Delete Post  Reply With Quote 
Sorry, I couldn't resist.
quote:
Originally posted by Nanuq:
The hardest part of the process is getting the crocodile to donate the blood.


quote:
From the crocodilehunter.com:
Crikey, we’ve come a long way in our croc trapping technology since 1980. Australia Zoo’s International Crocodile Rescue allows me the freedom and engineering expertise to design, build, trial and utilize the most advanced trapping techniques in the world.
-Steve Irwin


http://tinyurl.com/bacqf

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DrConway
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posted 22 August 2005 03:44 PM      Profile for DrConway     Send New Private Message      Edit/Delete Post  Reply With Quote 
What, hopefully, will be the objective is to be able to synthesize the HIV drug after we get its structure. A buddy of mine is the MacGyver of chemistry. He can work out an organic synthesis for damn near just about anything using just common first-year lab chemicals; I bet if he knew about it he could work out the synthesis and make someone a pile of money.
From: You shall not side with the great against the powerless. | Registered: May 2001  |  IP: Logged
MyNameisLeo
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posted 22 August 2005 09:25 PM      Profile for MyNameisLeo     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
It correlates with cognitive functions, and so to whatever degree you believe an animal suffers under any given treatment, it's going to suffer more if it has a larger brain to recognize that suffering.

Dangerous assumption. Brain size has only a rough correlation to cognitive function. The human brain only needs about 10% of its mass, I believe. Further, "suffering" doesn't require much cognitive function. Just because we can't understand much about reptiles, we mammals needn't assume we're vastly superior to them.

quote:
It's why nobody talks about cruelty to plants, right? The assumption that plants lack any self-awareness or consciousness?

Actually, there has been some interesting research in this area. Evidently, plants do *respond* to having neighbouring plants killed. To call it "consciousness" is pushing it but, still, it's best to tread softly.

As far as the crocodile blood goes, though, once a decent amount is collected, why can't it be grown in the lab thereafter? It's certainly doable for DNA (via polymerase chain reactions) so why not for other types of cells?

PETA is supported by a vast spectrum of people, not all of whom will appreciate the reference to "animal rights kooks." There was a time, not that long ago, when people talked about "women's rights kooks" and even more recently "gay people's kooks."


From: SWBC | Registered: Aug 2005  |  IP: Logged
chubbybear
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posted 22 August 2005 09:46 PM      Profile for chubbybear        Edit/Delete Post  Reply With Quote 
quote:
Originally posted by MyNameisLeo:
PETA is supported by a vast spectrum of people, not all of whom will appreciate the reference to "animal rights kooks." There was a time, not that long ago, when people talked about "women's rights kooks" and even more recently "gay people's kooks."
PETA loses credibility when they equate farming with the enslavement of African people and the genocide of Aboriginal people. http://tinyurl.com/axec6

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MyNameisLeo
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posted 22 August 2005 10:26 PM      Profile for MyNameisLeo     Send New Private Message      Edit/Delete Post  Reply With Quote 
Of course they do! Likewise when they compare factory farming to the Holocaust. PETA does lots wrong, no question about that. But, still, believing in animal rights shouldn't make one a "kook."
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MyNameisLeo
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posted 22 August 2005 10:26 PM      Profile for MyNameisLeo     Send New Private Message      Edit/Delete Post  Reply With Quote 
Of course they do! Likewise when they compare factory farming to the Holocaust. PETA does lots wrong, no question about that. But, still, believing in animal rights shouldn't make one a "kook."
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swirrlygrrl
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posted 23 August 2005 11:37 AM      Profile for swirrlygrrl     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Dangerous assumption. Brain size has only a rough correlation to cognitive function...Further, "suffering" doesn't require much cognitive function.

Word.

People tend not to worry a lot about the pain caused to animals when the animals aren't cute and in their sight (usually must have both conditions).

Some people don't like the correlation (and PETA has a habit of discussing at times in the most broad, offensive, aggressive, confrontational terms, which I don't think is particularly effective or helpful), but human history is ripe with examples of people declaring that those who are different, other in some way, are less worthy of consideration. Currently, we look back on a lot of their logics and rationales and actions as wrong, or mistaken.

Some animal rights activists think humans should see all pain as valid, regardless of whether it is human or animal. They think we are, or should, be moving away from such distinctions. I have my own personal opinions, but again, I think that people should be honest about what they think and why - justifying things in bad science isn't needed. Why not simply say "they're a crocodile, and regardless of whether they feel pain, or how much of it they feel, I value a human life over their life, or their pain?"

I'll end with some Shakespeare.

quote:
I am a Jew. Hath not a Jew eyes? hath not a Jew hands, organs, dimensions, senses, affections, passions? fed with the same food, hurt with the same weapons, subject to the same diseases, healed by the same means, warmed and cooled by the same winter and summer, as a Christian is? If you prick us, do we not bleed?
if you tickle us, do we not laugh? if you poison
us, do we not die? and if you wrong us, shall we not revenge?

From: the bushes outside your house | Registered: Feb 2002  |  IP: Logged
Mr. Magoo
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posted 23 August 2005 02:06 PM      Profile for Mr. Magoo   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
quote:
Word.

People tend not to worry a lot about the pain caused to animals when the animals aren't cute and in their sight (usually must have both conditions).


So, simple question then: would you kill an insect? A mosquito, or a yellowjacket perhaps?

If you believe in "animal rights", do you believe in them for insects as well?

If the answer is "no" to either of these, are you certain it isn't no because insects have such tiny little brains, such as they are, and you're making the same assumptions about brain size and cognitive function that I am?


From: ø¤°`°¤ø,¸_¸,ø¤°`°¤ø,¸_¸,ø¤°°¤ø,¸_¸,ø¤°°¤ø, | Registered: Dec 2002  |  IP: Logged
swirrlygrrl
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posted 23 August 2005 02:29 PM      Profile for swirrlygrrl     Send New Private Message      Edit/Delete Post  Reply With Quote 

Grow up, Magoo. This isn't about me, or at least I never made it about me. If you want to know my opinions on the issue, you could ask, but I've never stated them, in part because I don't think its black or white - zealots on both sides are problematic (as is usually the case).

But, since you asked, I do kill mosquitos and wasps. Well, actually, I'm squeamish, so in the case of wasps, I run around in a girly fashion, or ask someone else to kill them if they hang around for a bit. And I do so because mosquitos suck my blood and could result in the contraction of West Nile Virus or such, let alone itchy bites, while wasps are aggressive and I've been stung on many occassions. Both are self defense. I could probably kill a human in self defence as well, if I had to.

Much better examples - do I kill honeybees, or harmless spiders like daddy long legs, or the house centipedes in my apartment which are creepy but not a problem in any other sense, and if so, why? How do I justify that?


From: the bushes outside your house | Registered: Feb 2002  |  IP: Logged
Mr. Magoo
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posted 23 August 2005 03:43 PM      Profile for Mr. Magoo   Author's Homepage     Send New Private Message      Edit/Delete Post  Reply With Quote 
Actually I thought my question was fine as-is. I'm not sure why you're taking umbrage with it.

Anyone who thinks that all animals have "rights" (whether that refers to you or not) either has to say that insects, as animals, also have rights, or else they have to make an exception for insects.

And without putting any words in their mouths, I'd guess that if they make an exception for our smallest animals, it's on the grounds that they lack the sentience and self-awareness that we tend to believe are factors in any organism's ability to suffer. An unaware animal may react to a stimulus, but we don't really think of them, typically, as suffering. Same with plants, as I noted. We know plants are alive, but as they don't have a measurable "brain" we assume them to be unconscious and unaware.

Anyway, I just thought I'd take the chance to needle at one of my bugbears: when I suggest that for the most part consciousness, sentience, and the ability to suffer are proportional to brain size, someone will inevitably suggest that "there's much I don't know".

This may be true, but does it cut the other way?

In other words, if I'm biting off more than I can chew by suggesting that animals with tiny brains don't suffer the way a primate would, for example, then would someone be similarly biting off more than they can chew by suggesting that insects wouldn't suffer? After all, we'd both be making pretty much the same assumption.

Similarly, if you'd kill an insect, why not a shrimp? One lives under your porch, the other under the waves, but otherwise, pretty much the same thing.

I'm certainly not interested in any animal-rights types (and I'm not referring to you) who'd tell me that killing a fly and killing a shrimp are vastly different acts, and that one is morally worse than the other.


From: ø¤°`°¤ø,¸_¸,ø¤°`°¤ø,¸_¸,ø¤°°¤ø,¸_¸,ø¤°°¤ø, | Registered: Dec 2002  |  IP: Logged

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